Experimental Model of Intervertebral Disk Mediated Postoperative Epidural Fibrosis
نویسندگان
چکیده
منابع مشابه
An experimental model to study contrast enhancement in MR imaging of the intervertebral disk.
MR imaging after IV gadolinium-DTPA administration has demonstrated contrast enhancement in traumatized lumbar intervertebral disks. To characterize the morbid anatomy that correlates with the contrast enhancement, we developed a canine model of traumatized intervertebral disks. Diskectomy was performed with a nucleotome and the spines were imaged biweekly with MR and Gd-DTPA. The spines were s...
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STUDY DESIGN Agreement study. PURPOSE To validate the interrater reliability of the histopathological classification of the post-laminectomy epidural fibrosis in an animal model. OVERVIEW OF LITERATURE Epidural fibrosis is a common cause of failed back surgery syndrome. Many animal experiments have been developed to investigate the prevention of epidural fibrosis. One of the common outcome ...
متن کاملEffects of 4% Icodextrin on Experimental Spinal Epidural Fibrosis.
AIM The aim of this experimental study was to investigate whether spinal epidural 4% glucose polymer solution is effective in the prevention of postoperative fibrosis. MATERIAL AND METHODS Twenty eight adult Wistar albino rats were randomly divided into two equal groups, including treatment and control. Both groups underwent L1 vertebral total laminectomy to expose the dura. Topical treatment...
متن کاملDifferences in Epidural Pathology between Cervical and Thoracolumbar Intervertebral Disk Extrusions in Dogs
BACKGROUND Although the basic pathophysiology is the same in both cervical and thoracolumbar intervertebral disk (IVD) extrusions, there are considerable clinical differences that have only been partially explained. HYPOTHESIS/OBJECTIVES The epidural inflammatory response differs between cervical and thoracolumbar IVD extrusions. ANIMALS Fifty-five dogs with cervical and 80 dogs with thorac...
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Disk inflammation in children is believed to result from infection, and Staphylococcus aureus is reported to be the organism most commonly isolated from cases of intervertebral disk infection. A case of disk inflammation caused by the unusual pathogen Kingella kingae is described. The antibiotic susceptibility of other K. kingae isolates and the clinical features of 11 other previously reported...
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ژورنال
عنوان ژورنال: Annals of Neurosciences
سال: 2016
ISSN: 0972-7531,0976-3260
DOI: 10.1159/000443564